17 Views· 11/04/22· Alternative Medicine
Ivermectin Clarification
Ivermectin, is a Food and Drug Administration (FDA)-approved antiparasitic drug,
https://www.covid19treatmentgu....idelines.nih.gov/the
https://www.covid19treatmentgu....idelines.nih.gov/theivermectin/
Direct from official FDA site
used to treat several neglected tropical diseases,
including onchocerciasis, helminthiases, and scabies.
For these indications, ivermectin has been widely used and is generally well-tolerated
Ivermectin is not approved by the FDA for the treatment of any viral infection.
Proposed Mechanism of Action and Rationale for Use in Patients With COVID-19
(in vitro studies)
suggest that ivermectin acts by,
Inhibiting host importin nuclear transport proteins
Interfere with SARS-CoV-2 spike protein attachment to the human cell membrane
Some studies of ivermectin have also reported potential anti-inflammatory properties
Shown to inhibit replication of SARS-CoV-2 in cell cultures
COVID-19 medical misinformation policy
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Claims that Ivermectin and Hydroxychloroquine are safe to use in the prevention of COVID-19
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Claims that Ivermectin and Hydroxychloroquine are safe to use in the prevention of COVID-19
Monitoring, Adverse Effects, and Drug-Drug Interactions
The FDA first issued a warning in April 2020 that ivermectin intended for use in animals should not be used to treat COVID-19 in humans. This warning was updated and reiterated in 2021.
https://www.fda.gov/consumers/....consumer-updates/why
FDA, Recommendation
The Panel recommends against the use of ivermectin for the treatment of COVID-19, except in clinical trials
The Panel will continue to review emerging data on ivermectin use, including the results from 2 large, ongoing randomized controlled trials.
Clinical Trials
Several clinical trials evaluating the use of ivermectin for the treatment of COVID-19 are currently underway or in development.
Please see ClinicalTrials.gov for the latest information.
Bangkok
Egypt
Malaysia
Is this one of the two?
https://www.principletrial.org..../news/ivermectin-to-
Ivermectin to be investigated in adults aged 18+ as a possible treatment for COVID-19 in the PRINCIPLE trial
23 June 2021
Time line
https://www.principletrial.org..../news/the-principle-
1 Comments
BHInnx
2 years ago